Do Drugs for Diabetes Actually Cause Pancreatic Cancer?
Posted By Dr. Mercola | September 22 2011 |
Researchers have found a possible link between two drugs for Type 2 diabetes, Januvia and Byetta, and cancers of the pancreas and thyroid. The research was done in the wake of several studies in animal models that suggested the drugs might promote growth of the ducts in the pancreatic gland.
Both drugs work by stimulating the hormone glucagon-like peptide 1, or GLP-1. The actions of GLP-1 may increase the rate of formation of cells that line the pancreatic ducts, which could lead to pancreatitis.
According to Drugstore News:
"Comparing Januvia and Byetta with four others that constituted a control group, the researchers found a six-fold increase in the odds ratio for reported cases of pancreatitis, as well as a nearly threefold increase in the risk of pancreatic cancer. In addition, they found a statistically significant increase in the risk of thyroid cancer among patients taking Byetta, but not among those taking Januvia."
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